NetScaler 10.0 Build 73.5
We are having intermittent timeout issues with the RPC LB VIP, to replicate the issue we can open a new Outlook message, click on "To" to see the GAL and it errors.
Our Exchange RPC timeouts are configured as default (15mins).
The RPC LB VIP has a Persistence time out (Method and Persistence tab) of 150mins (was 2mins initially).
The RPC LB Service Group has Idle Timeouts (Advanced tab) of Client=9000secs and Server=9000secs
It appears to definitely be something with the NS config as if we bypassed the NS for a couple of days it didn't appear to be an issue.